Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease Published: June 26, 2019 DOI: https://doi.org/10.1016/j.neuron.2019.05.035 Interview with Ted Dawson discussing his lab’s demonstration that misfolded α-synuclein which can move from the stomach to the brain and cause physical and cognitive symptoms.: https://www.the-scientist.com/news-opinion/mouse-model-shows-how-parkinsons-disease-begins-in-the-gut-66048
Tag: Neuroscience
TREM2 function impedes tau seeding in neuritic plaques
Cheryl E. G. Leyns, Maud Gratuze, Sneha Narasimhan, Nimansha Jain, Lauren J. Koscal, Hong Jiang, Melissa Manis, Marco Colonna, Virginia M. Y. Lee, Jason D. Ulrich & David M. Holtzman Nature Neuroscience (2019) Abstract Variants in the triggering receptor expressed on myeloid cells 2 (TREM2) have been associated with increased risk for sporadic, late-onset Alzheimer’s […]