Transneuronal Propagation of Pathologic α-Synuclein from the Gut to the Brain Models Parkinson’s Disease Published: June 26, 2019 DOI: https://doi.org/10.1016/j.neuron.2019.05.035 Interview with Ted Dawson discussing his lab’s demonstration that misfolded α-synuclein which can move from the stomach to the brain and cause physical and cognitive symptoms.: https://www.the-scientist.com/news-opinion/mouse-model-shows-how-parkinsons-disease-begins-in-the-gut-66048
Prof Dr Margie Sharpe
TREM2 function impedes tau seeding in neuritic plaques
Cheryl E. G. Leyns, Maud Gratuze, Sneha Narasimhan, Nimansha Jain, Lauren J. Koscal, Hong Jiang, Melissa Manis, Marco Colonna, Virginia M. Y. Lee, Jason D. Ulrich & David M. Holtzman Nature Neuroscience (2019) Abstract Variants in the triggering receptor expressed on myeloid cells 2 (TREM2) have been associated with increased risk for sporadic, late-onset Alzheimer’s […]
Suppression of Tinnitus in Mice Moving to Clinical Trials
“Sometimes scientists can’t discern if something went wrong in an animal model until clinical results show inconsistency. That is why we always exercise caution [about interpreting results with animal models] before we see the confirmation from clinical findings involving people,†Zhang said. Zhang is also a member of the ATA Board of Directors and former chair of the ATA’s Scientific Advisory Committee.
The takeaway Frenzel goggles
A Fresnel-based device
Hearing loss and diabetes
“It is vital that diabetics should have their hearing tested as part of their diabetes management programme to implement preventive health and hearing conservation strategies.
Scientists ‘Clear’ Alzheimer’s Plaque From Mice Using Only Light And Sound
Light was just one way to trick the parts of the brain into humming in the key of gamma. Sounds can also manage this in other areas.